The seven-time Nigeria League champions, Enyimba International, will start the defence of their league shield away to Dolphins FC in Port Harcourt.
While the Aba Elephants won top prize last term, Dolphins escaped relegation by the whiskers after a final win away to Shooting Stars.
The draws for Match Day 1 fixtures of the 2015/16 Nigeria Professional Football League Season, NPFL were conducted on Sunday in Kaduna at the on-going pre-season Super Four tourney.
As reflected in the draws, the Premier League will be kick starting in Lagos as newly promoted Ikorodu United will play host to Abia Warriors.
The other team from Lagos, MFM FC, which also just secured promotion, will have their baptism in the elite division with an away game against CAF Confederation Cup campaigners, Nasarawa United.
One of the biggest pairing for Week 1 is the clash between Kano Pillars and Enugu Rangers.
The new season is to kickoff on February 21, 2016.
Match day 1 Fixture of the 2015/2016 NPFL season
Ikorodu Utd vs Abia Warriors
Giwa vs FC Ifeanyi Uba
3SC vs Lobi Stars
Plateau Utd vs Niger T.
Heartland vs W. Wolves
Pillars vs Rangers
Elkanemi vs Wikki. T
Nasarawa Utd vs MFM FC
Dolphins vs Enyimba
Sunshine Stars vs Akwa Utd