Two former world No.1s, Roger Federer and Maria Sharapova have been sent packing from the 2018 US Open.

Federer, the current world No.2 was shocked by John Millman, 3-6, 7-5, 7-6, and 7-6 in three hours and 34 minutes.

Ranked 55 in the world, the 29-year-old did what he had never done – beat a player in the top 10 of the ATP ranking.

Federer thus lost out in his quest for a 13th consecutive quarterfinal berth at Flushing Meadows and he will look back at his 76 unforced errors as the main reason he has had to leave the stage. This follows his quarterfinal defeat at Wimbledon.

“I felt like a deer in the headlights, to begin with; Roger had it on a string,” Millman revealed in the post-match interview.

“He was manipulating me around the court, but I got out of a tough second set and really found my feet.” And he never gave up.

“I’ve got to control the controllables, I said that before I went out and played. The one thing I can control is the fight in me. I have always done that.”

His reward is a clash with current Wimbledon champion, Novak Djokovic.

For Sharapova, defeat was from an inspired Carlos Suarez Navarro, who gave herself a stellar 30th birthday gift.

Navarro revealed she did not want to experience the same feeling as last year when she bowed out at the same stage to Venus Williams.

“When I woke up, I just was thinking on that match,” she said in her post-match interview.

“I just wanted to win. I mean, was a really good present for me. I was playing also last year same day against Venus Williams, and I lost. This time I don’t (didn’t) want to feel like last year. I wanted to have a happy birthday, and I have it.”

She is up next against Madison Keys.