The Gunners defeated their London rivals, 5-2.
Arsenal, though starting from behind, finished strongly in the first half and then consolidated in the other half.
Former Gunner, Emmanuel Adebayor, scored a 10th minute goal to shoot Tottenham Hotspurs ahead, but went into a rash tackle just eight minutes later to earn a red card.
Not too long thereafter, Per Mertesacker pulled the Gunners level with a bullet header in the 24th minute, while Lukas Podolski scored with an assist from William Gallas on 42 minutes, and Olivier Giroud, who continues to enjoy a fine scoring form, also scored.
Arsenal were not done as more goals came with the resumption of play in the second half. Santi Cazorla scored his first League goal at the Emirates to pull Arsenal further ahead on 60 minutes, before Theo Walcott completed the humiliation in added time, when he profited from good play by Oxlade Chamberlain, to score a fifth.
Gareth Bale had earlier pulled one back in the 71st minute.