Malaria vaccine passes trial test

Malaria vaccine that uses a weakened form of the parasite has passed a critical milestone in human safety trials.

According to Africa Review, doctors used a genetically modified form of malaria that is unable to cause a full infection in people.

Trials was published in the journal Science Translational Medicine which suggested it was safe with a good immune response.

Tropical disease experts described the findings as “promising”.

The malaria parasite goes through multiple stages both in mosquitoes and inside the human body.

The team at the Centre for Infectious Disease Research, in Seattle, deleted three genes from the parasite so it could not infect liver cells.

The idea is that “infecting” people with the weakened parasite will expose the immune system to malaria, but the parasite will not be able to complete its lifecycle to cause disease.

Ten people took part in the safety trials. No-one went on to develop the disease and there were no severe side-effects to the treatment.

The patients’ antibodies were then given to mice, which showed greater immunity when they were deliberately infected with malaria.

Sebastian Mikolajczak, one of the researchers, said: “The clinical study now shows that the vaccine is completely attenuated in humans and also shows that even after only a single administration, it elicits a robust immune response against the malaria parasite.

“Together these findings are critical milestones for malaria vaccine development.”


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  • Fred Duke

    Will the West and their gigantic pharmaceutical industry allow this vaccine to go through?

    • Anonymous

      Why can’t your people come up with something without western aid?

      • Fred Duke

        Pls don’t go there. When I said West with capital W, I mean the West. I didn’t say western Nigeria. However if you’re referring to the same West, then im puzzled. How many malaria drugs are discovered from herbs and plants from Africa? How many times have Africans at home or abroad come so close to making a substantial recovery, only for the West to block it, rubbish it, and later use it in their labs to “make a groundbreaking discovery”? If the West is still strange to you, ask the person close to you. I’m an African and we know all the game the West plays…using our resources to make discoveries… But always blocking us from doing so, using some ” methodical ” stories.

        • Anonymous

          How are they blocking you? Will they hamper your concept if you build a world class technology? Please direct your frustration to your inept government.

          • Fred Duke

            Return the loot that you people encouraged the dictators and even current thieves to cart away to your countries. And then allow us the ordinary citizens to use the funds and develop ourselves. Whenever we need help, we would call you. I understand that no country can do it alone, but as long as you people keep providing safe haven for these criminals, then Africa would still be perceived as being inept. It is the leaders that you people support, not us the citizens.

          • Anonymous

            Is looting government resources not embedded in you’ll DNA? You will do worse if opportunity calls. Africa is cursed.

          • Fred Duke

            Maybe. But you people underdeveloped Africa. You merged us in Nigeria with people that we have nothing in common with, just because of you people’s greed. You merged us with people whose religion encourage them to kill. And they loot at will too. All those loots are carted to the West and you’re here policing me. Get a life Sir.

          • Anonymous

            You guys tend to throw conniption when you hear the truth. Social revolution is the only panacea that will redress Africa’s perpetual instability and poverty.

          • Fred Duke

            Social revolution that you guys stifle all the time. Whether KGB or American spy, i dont have your time. After all, all you keep doing is imposing stooges on us that obey your last command in the name of national security. As long as the West plunders Africa with the helpbof these anti-democratic forces, do you people care?

          • Fred Duke

            These same stooges are the ones carting away our resources to foreign lands, subjecting pregnant women and children to avoidable poverty and deaths. These same crooks and dictators develop foreign countries with stolen resources. Why is it so hard for those loots to be repatriated? There’s no willpower. Nay, your entities would be left empty because it is the west that have conspired with dictators to underdevelop Africa.

  • Peter_Edo

    This is good news…